Using the data of the 500 hPa pentad anomaly of 14 winters (1971-1984) in the Northern Hemisphere,the geographical distribution of the general circulation anoma-lies in the Northern winter is analysed. The effects of the 30-50 day low-frequency fluctuation and quasi-14 day fluctuation on the persistent anomalies in their evolution are studied. Results show that the time scale of the persistent anomalies is mainly associ-ated with the 30-50 day low-freqency fluctuation. It is found that Alaska is the key region of not only the persistent anomalies but also the 30-50 day low-frequency fluc-tuation. The persistent circulation anomalies and weather-climate anomalies are chiefly dominated by the 30-50 day low-frequency fluctuation.