This paper studies the response of the coastal temperature over Jiangsu(JS) to the warming over the Northern Hemisphere(NH) during recent 35 years using two methods, i.e. the principal component analysis and regression estimate. According to the condition of mean warming over the NH, the possible warming amplitudes and their dependabilities over the JS region are estimated for the future climate. The results are as follows: (1) responses for the trend of summer temperature and inter annual fluctuation to the warming over the NH have great uncertainty; (2) except summer the changes of other season and annual mean temperatures are significant in response to the NH warming with winter being most sensitive, and under the NH warming of 1℃, the seasonal warming over the JS region may generally reaches 0.7～0.8℃ with the largest being 0.9℃ in winter; And (3) sensitive and dependable areas are located in Xu Huai Yian areas and the coastal belt respectively.