The Hunshandake sand region is an area very sensitive to the climatic changes related to human activities. The tendency of climatic variations revealed in this study exhibits that the cold/warm and dry/wet periods occurred alternatively during the 1960s, warm and humid periods in the 1970s, and warm and arid periods during the 1980s. There exists a significant periodical oscillation in the meteorological factors related to desertification, with its duration varying from 2-4 to 6-8 years. A statistical model is established for various factors including aridity, and annual rainfall amount.The climatic tendency in the sand region predicted for 1990 and 1991 in terms of Chebyshev polynomials,ie,warm,humid 1990 and warm,arid 1991,is consistent with what actually happened.